PROTON PUMP FUNCTION IN GASTRIC ACID SECRETION

The proton pump functions a critical role in gastric acid {secretion|. The pump is an integral membrane protein located at the apical surface of parietal cells in the stomach lining. It catalyzes the active movement of protons (H+) from the cytoplasm of parietal cells into the gastric lumen, resulting to the acidification of the stomach contents.